Genomic Profiling
OUR PLATFORM
We deliver a broad range of sequencing services—tumor tissue and liquid DNA profiling, somatic and germline testing, tumor-normal matched profiling and RNA sequencing—all of which empowers you to make data-driven decisions for your patients.
COMPREHENSIVE AND COMPLEMENTARY SEQUENCING
One partner. Smart Insights.
We offer worldwide access to our comprehensive genomic profiling services and data-driven solutions to help inform patient care and advance precision oncology decisions.
Download our case studies to see how we support sequencing for research, clinical trials, and sponsored testing.
COMPREHENSIVE AND COMPLEMENTARY SEQUENCING
We offer worldwide access to our comprehensive genomic profiling services and data-driven solutions to help inform patient care and advance precision oncology decisions.
Download our case studies to see how we support sequencing for research, clinical trials, and sponsored testing.
Our Comprehensive Test Offerings
STAR Health Network xT
Targeted Panel of
648 genes
Solid Tumor + Normal Test
Gene List
STAR Health Network xF
Targeted Panel of
105 genes
Liquid Biopsy Test
Gene List
STAR Health Network xE
19,000+ genes
Whole Exome Test
Download validation summary
STAR Health Network xG
(Powered by GeneDx)
88-gene and 52-gene germline panels
xG+ (extended hereditary cancers)
xG (common hereditary cancers)
Gene List
DNA + RNA Whole Transcriptome Sequencing
29% more patients were identified with a unique clinically actionable fusion matched to a targeted therapy, compared to DNA sequencing alone.1
Solid Tumor and Normal Matched DNA Sequencing
28% reduction in somatic false-positive calls, improving accuracy compared to tumor-only analysis.2
Incidental Germline
Findings
7% of patients were found to harbor pathogenic or likely pathogenic germline variants across multiple cancer types and are indicated for confirmatory germline testing, per high risk assessment guidelines.3,4
Concurrent Solid Tumor
and Liquid Biopsy Testing
9% of patients had unique actionable variants found in liquid biopsy that were not detected in solid tumor alone.5
Clinical Data Integration
96% of patients matched to a clinical trial when clinical data was combined with STAR Health Network NGS.2
Automatic Conversion Option
In the event of insufficient tumor tissue, convert to liquid biopsy testing for rapid genomic results.
Algorithmic Tests
We provide advanced patient insights without the need for additional tissue.
1 Based on a retrospective study involving a cohort of randomly selected patients with tumor types including low grade glioma, sarcoma, glioblastoma, bladder, NSCLC and biliary tract cancer. Michuda J, Park BH, Cummings AL, et al. Use of clinical RNA-sequencing in the detection of actionable fusions compared to DNA-sequencing alone. JCO. 2022;40(16_suppl):3077.
2 Based on a retrospective study involving a cohort of randomly selected patients with tumor types including brain, breast, colorectal, lung, ovarian, endometrial, pancreatic and prostate cancer. Beaubier N, Bontrager M, Huether R, et al. Integrated genomic profiling expands clinical options for patients with cancer. Nat Biotechnol. 2019;37(11):1351-1360.
3 Based on a retrospective study involving a cohort of randomly selected patients treated in geographically diverse oncology practices in the US with tumor types including bladder, brain, lung, cholangiocarcinoma, head and neck, breast, ovarian, pancreatic, prostate, endometrial and colorectal. Yap TA, Ashok A, Stoll J, et al. Prevalence of germline findings among tumors from cancer types lacking hereditary testing guidelines. JAMA Network Open. 2022;5(5).
4 NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) for Genetic / Familial High- Risk Assessment: Breast, Ovarian, and Pancreatic V.2.2022 © National Comprehensive Cancer Network, Inc. 2022.
5 Based on a retrospective study involving a cohort of randomly selected patients with breast cancer, CRC, NSCLC, and prostate cancer. Mackay M, Mitsiades N, Chae YK, et al. Dual tissue and plasma testing to improve detection of actionable variants in patients with solid cancers. JCO. 2022;40(16_suppl):3017.
Clinical support tools
STAR Health Network Hub
Our online Hub allows you secure, fast, reliable access to patient report status and results. View interactive and in-depth next-generation sequencing results in the context of a patient’s clinical history, filterable treatment applications and clinical trials, and PDFs of all STAR Health Network reports. You will also have access to our near real-time support tool that connects you with up-to-date treatment options and relevant insights derived from real-world clinical evidence across millions of de-identified patient records, our vast library of molecular profiling data, and our advanced analytics and machine-learning algorithms.
The STAR Health Network Order Summary
After processing your entire order, we produce an order summary highlighting all key findings from the xT and xF tests along with additional tests like HRD and TO, including actionable treatments, microsatellite instability (MSI) status, and tumor mutational burden (TMB) that can be quickly translated into cancer patient care. Our reports are also embedded with STAR Health Network Insights, patient-specific insights derived from real-world evidence to empower physicians with the necessary data to improve patient care.
SMART REPORTS
STAR Health Network is the first genomic sequencing company to incorporate both Memorial Sloan Kettering Cancer Center’s OncoKB and NCCN Content into smart clinical reports. MSK OncoKB & NCCN are two of the most robust oncology databases in the world. With the integration of these trusted sources, you can:
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Optimize treatment plans for your patients
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Stay updated with the latest indications and recommendations
Integration and Connectivity Solutions
With a dedicated team of integration experts, we offer a fully interoperable solution for clinical ordering and returning results back into an institution’s health IT systems. We can transform our report into discrete genomic data that can be loaded directly into your system(s) in industry standard HL7 format. In addition, we collaborate with partners to offer a fully interoperable structured result file format which can be parsed and loaded into an institution’s data ecosystem to power their precision medicine program.
To ease the clinical ordering workflow, we support the automation of appropriate and secure data sharing to power your precision medicine program with STAR Health Network clinical support and advanced analytics. If you have already ordered STAR Health Network through paper or online methods, we can historically backfill prior results into your system(s).
We understand the power of analytics and the positive impact it has on clinical support. Contact us today.